Mediterranean Decision Support System for Marine Safety is dedicated to the strengthening of maritime safety by mitigating the risks and impacts associated to oil spills. MEDESS-4MS capitalizes on existing pan-European frameworks and embraces recent advances and important developments in oceanography in the Mediterranean area. MEDESS-4MS aims to deliver an integrated operational multi model oil spill system in the Mediterranean by gathering and analyzing met-ocean data as well as data related to ship traffic, ship operations and sensitivity mapping. This data will be provided to well established oil spill monitoring and forecasting systems, thus, providing an invaluable tool regarding the early detection and efficient control of the oil spill at early stages.